In vivo Optical Imaging / Intravital Microscopy
نویسندگان
چکیده
منابع مشابه
In Vivo MRI and Intravital Optical Microscopy of Window Chambers in Mice
A. F. Gmitro, S. Moore, R. Gatenby Department of Radiology, University of Arizona, Tucson, AZ, United States, College of Optical Sciences, University of Arizona, Tucson, AZ, United States, Biomedical Engineering, University of Arizona, Tucson, AZ, United States Introduction: MRI of mouse models is a powerful method of investigation in cancer biology. It is used routinely to study anatomic, phys...
متن کاملIntravital microscopy
Intravital microscopy is an extremely powerful tool that enables imaging several biological processes in live animals. Recently, the ability to image subcellular structures in several organs combined with the development of sophisticated genetic tools has made possible extending this approach to investigate several aspects of cell biology. Here we provide a general overview of intravital micros...
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We report optical-resolution photoacoustic microscopy (OR-PAM) for in vivo imaging of amyloid plaques in an Alzheimer's disease mouse model. Validation using conventional fluorescence microscopy and multiphoton microscopy shows that OR-PAM has sufficient sensitivity and spatial resolution to identify amyloid plaques in living brains. In addition, with dual-wavelength OR-PAM, the three-dimension...
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Corneal neovascularization leads to blurred vision, thus in vivo visualization is essential for pathological studies in animal models. Photoacoustic (PA) imaging can delineate microvasculature and hemodynamics noninvasively, which is suitable for investigating corneal neovascularization. In this study, we demonstrate in vivo imaging of corneal neovascularization in the mouse eye by optical-reso...
متن کاملIntravital microscopy
In principle, there is little difference between conventional microscopy methods and intravital microscopy; in practice, however, there are significant differences in the way images are acquired and processed and a number of unusual features are associated with the microscope mechanics and other accessories. This note describes the approaches that we have developed over the last few years at GC...
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ژورنال
عنوان ژورنال: Journal of Biophotonics
سال: 2017
ISSN: 1864-063X
DOI: 10.1002/jbio.201770066